The Belgian completed a £75million move from Everton this summer to become the most expensive Premier League transfer of the window.
Lukaku has been tasked with leading the line for the Red Devils this season and has big boots to fill.
Zlatan Ibrahimovic netted 28 times in all competitions last term and Lukaku will need to be reaching similar heights if Jose Mourinho wants to be challenging for titles.
And United legend Yorke believes the 24-year-old has what it takes to make it at Old Trafford.
Romelu Lukaku has been backed to score 20-plus goals for Manchester United
He just needed a platform to go and showcase his talent and in my mind he will definitely get us 20-plus goals this season. It is dead-on certain.
Dwight Yorke
"Since leaving Chelsea, he has been one of most eye-catching strikers out there," he told talkSPORT.
"I came from a similar position when I went from Aston Villa to United and people will always cast doubt over whether you have the quality, but this guy has got it all.
"He just needed a platform to go and showcase his talent and in my mind he will definitely get us 20-plus goals this season. It is dead-on certain.
"The price tag everyone gets bogged down on but that is just the way the game has gone. He just needs to be calm.
GETTY
Romelu Lukaku celebrates scoring for Manchester United against Real Madrid
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"He is good enough, he is at the club he wants to be at, he has got lots of people there who will support him, his friends are there, and he will do just fine."
Lukaku scored for United in last night's 2-1 defeat to Real Madrid in the Uefa Super Cup.
And he'll be hoping to get his Premier League campaign off to a winning start with a goal when United host West Ham on the opening day on Sunday (4pm).
