Wenger has made 11 changes in all from the side which beat Everton on Sunday but there are just two changes from the makeshift side that won against Red Star Belgrade last Thursday.
Matt Macey makes his debut in goal with Mathieu Debuchy, Mohamed Elneny and Rob Holding in the back three.
Jack Wilshere starts in central midfield alongside Francis Coquelin. Alex Iwobi and Theo Walcott support Olivier Giroud in attack.
Norwich make four changes for the game tonight, with James Husband, Mario Vrancic, Josh Murphy and Nelson Oliveira coming into the XI.
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