Liverpool cruised to a 4-0 victory over the Gunners following goals from Roberto Firmino, Sadio Mane, Mohamed Salah and Daniel Sturridge.
Wenger faced protests from fans last season before penning a new two-year deal this summer.
And more disquiet was heard from the travelling support following the Gunners’ battering.
But the beleaguered Frenchman has pleaded for unity.
He said: “The consequences are that the confidence drops, we need everyone to keep belief and focus.
“If some people feel as if I am the problem then I am sorry that I am the problem but we want our fans to be with us even in a losing performance like that.
“The only thing we can do is come back and give them a better performance.”
When quizzed about the display from his players, Wenger pulled no punches.
He added: “It was not good enough, we were beaten everywhere physically and in the end we we made it easier for them, we made unneeded mistakes.
"Mentally it was difficult. A very disappointing performance, it was disastrous.
“But it is not good to become too emotional after the game.
“There are some reasons behind it that we have to analyse but the players now go on an international break.
“We have done recently well in the big games. That is why today is even more disappointing."
