That’s according to former player turned pundit Martin Keown who says the Manchester City star is the top-flight’s deadliest marksman.
Lukaku and Morata have both impressed since signing for Manchester United and Chelsea respectively in the summer.
Meanwhile Kane - who bagged a brace against West Ham on Saturday - has found his shooting boots after a sluggish start to the season.
But Keown is adamant Aguero is still the top dog after six years in the top flight.
“Sergio Aguero would be the toughest opponent of these four strikers,” he told the Daily Mail.
“He drifts past defenders as if they are not there. He is icy cool, looks certain to score every time he is through on goal and is capable of spectacular strikes.
“Romelu Lukaku is immensely powerful but if you can match his pace and power you can bring him under control.
“Harry Kane is intelligent, dogged in the challenge and deceptively quick. His right boot is a thunderbolt so you must close him down quickly.
“Alvaro Morata has good movement and is benefiting from the chances supplied by this creative Chelsea team. To stop him, you need to cut off his supply line.
“But to get the better of Aguero is a different challenge altogether.
“Already one of the best, he has taken his game to another level.”
Aguero has scored 128 goals in 187 games for City since joining the club from Atletico Madrid in 2011.
