Stoke City stopper Butland replaces Joe Hart, the Three Lions’ regular first choice, for the last match of the campaign.
England have made sure of their place at the Russia 2018 finals, thanks to Thursday night’s last-minute win against Slovenia.
The pressure is off for the trip to Lithuania presenting Gareth Southgate with the opportunity to make changes.
Speaking about Butland, Southgate said: "He has been patient for his opportunity, his form has been good.
"It's a good opportunity for Jack."
Southgate believes England, who have conceded just three goals in nine qualifiers, are well served for goalkeeping options.
The likes of Jordan Pickford, Fraser Forster and Tom Heaton, who is currently injured, are expecting to be vying for places come next summer.
“We've got great competition for places,” Southgate said. “Joe was excellent the other night.
“We've got other good goalkeepers.”
