The Reds travel to Slovenia tomorrow night to play Maribor in the Champions League group stages.
A win for Liverpool could send them to the top of Group E ahead of La Liga side Sevilla.
The Reds come into the clash on the back of a tough draw with Manchester United on Saturday afternoon.
However, Klopp says there is no chance he’ll field a weakened team against Maribor.
When asked if he'll rotate his side, the Reds boss said: "No chance.
"This is the last place to do those things."
Klopp also hopes the game has a high intensity, with the German claiming that will help Liverpool secure a crucial three points.
"Yes in some moments they will be compact and together," Klopp added.
"We need to be ready for this. It needs to be a high intensity game."
Liverpool have drawn both of their Champions League games this season.
Klopp’s men were held at home by Sevilla in the opening clash, while Spartak Moscow thwarted Liverpool in the other.
Elsewhere in Group E this week, Sevilla travel to Spartak Moscow with the chance to extend their lead at the top of the table.
