Mauricio Pellegrino is up for the challenge of reining in Manchester United and may opt to start Virgil van Dijk in central defence, while striker Charlie Austin is available after a knock. Captain Steven Davis has called on Southampton fans to get behind them at a venue where United have won nine times in 12 visits. The trip to St. Mary’s is the first of six away games for United in the next month, and José Mourinho may seek to rotate his attacking options before the trip to CSKA Moscow, with Anthony Martial in form. Niall McVeigh
Kick-off Saturday 3pm
Venue St Mary’s Stadium
Last season Southampton 0 Manchester United 0
Referee Craig Pawson
This season G4, Y19, R2, 5.75 cards per game
Odds H 4-1 A 8-11 D 5-2
Southampton
Subs from McCarthy, Taylor, Stephens, Yoshida, Ward-Prowse, Boufal, Gabbiadini, Austin, McQueen, Bednarek, Hojbjerg, Gardos, Pied, Sims, Hesketh
Doubtful Van Dijk (match fitness)
Injured Targett (ankle, Oct)
Suspended None
Form DWDLW
Discipline Y5 R0
Leading scorers Austin, Davis, Gabbiadini, Tadic 1
Manchester United
Subs from Pereira, Romero, Tuanzebe, Lindelof, Smalling, Mata, Lingard, McTominay, Carrick, Herrera, Mitchell, Darmian, Young, Shaw
Doubtful None
Injured Pogba (hamstring, Oct), Ibrahimovic, Rojo (both knee, Dec)
Suspended None
Form WWWDW
Discipline Y5 R0
Leading scorer Lukaku 5