Manchester United have jetted off to Russia without Marouane Fellaini after the Belgian failed to recover from an ankle injury suffered at Southampton on Saturday.
Jose Mourinho's side left Manchester airport on Monday afternoon ahead of continuing their Champions League campaign against CSKA Moscow on Wednesday.
Fellaini was hurt in a tackle by Southampton's Shane Long in United's hard-fought 1-0 win and hasn't travelled with his team-mates.
Nemanja Matic, however, was on the plane after being a question mark following the game at St Mary's, as the Manchester Evening News reports.
Eric Bailly is also in the squad having served his European suspension and is in line to make his Champions League debut for the club.
United began their European campaign with a 3-0 victory over Basel and now have tricky away trips to face CSKA Moscow and Benfica.
There were 19 United players seen at the airport, one less than Mourinho's usual 20-man party.
Also not seen were Phil Jones, Antonio Valencia and Michael Carrick.
Bailly was one of the players singled out for praise by his manager following the weekend's Premier League victory at St Mary's Stadium.
Mourinho said: "Very good (Bailly and Jones) and also Smalling, we did for 20 minutes what the majority of the Premier League teams are doing, which is to play defensive with five at the back, we did that for 20 minutes.
"We had chances to kill the game, we had chances to score the second goal, we didn't.
"And then I honestly felt Southampton strong, I felt the manager enthusiastic, excited, risking, bringing two strikers like Gabbiadini and Austin to play direct to try to do a style that is also not normally their style and then I made the decision to bring on Smalling.
"And the team was solid, good solidarity, good organisation, good spirit and amazing points."
Juan Mata did not dwell long on the Southampton game, and is already focused on the long trip to Russia - the second of a run of six away games in seven fixtures.
Writing in his weekly blog, he said: "The three points keep us up in the table and with a high level of confidence, but that’s the past already "The schedule doesn’t allow for a break and we’re now focused on the Champions League.
"We pack our bags and travel to Moscow, where we play on Wednesday. It’s a long trip with two hours of time difference that will demand a quick adjustment.
"After winning the first game in the group stage it would be great to do the same in such a top clash.
"CSKA Moscow is a classic in European football. They won all their games in the two previous ties before the group stage, which they have started with an extraordinary victory in Lisbon.
"Needless to say, it’s going to be a very difficult game, as they all are in the Champions League anyway. We know how excited you are about this competition and we will give everything we have to live up to your expectations."
United players who've travelled to Russia
David de Gea
Sergio Romero
Joel Pereira
Eric Bailly
Chris Smalling
Daley Blind
Victor Lindelof
Axel Tuanzebe
Matteo Darmian
Ander Herrera
Nemanja Matic
Scott McTominay
Jesse Lingard
Ashley Young
Henrikh Mkhitaryan
Juan Mata
Romelu Lukaku
Anthony Martial
Marcus Rashford