Cazorla has quietly emerged as a creative hub for Wenger's side, racking up 32 assists in the Premier League, more than any other player since he joined the Gunners in the summer of 2012 from Spanish side Malaga.
The Spain international has received plaudits since his arrival on English shores.
And Wenger, who played him on the flanks upon the arrival of club's record signing Mesut Ozil two years ago, also says Cazorla's experience will be vital in a central role.
Wenger told Arsenal's website: "Yes (his permanent role will be in the middle). He's at an age where he has experience and where it's a bit more difficult on the flanks.
"His technical quality, vision and experience are very important centrally."
Wenger admitted he had his doubts over whether a diminutive Cazorla will be able to handle the physical demands of English football, but said the Spaniard's technical quality convinced him he was a gamble worth taking.
"You could question whether he was physically equipped to play in the tough Premier League.
"It's true that I had that doubt, but his quality was so big that I was ready to take that gamble.
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"His technical quality, his right foot, left foot, his availability, his vision and the quality of his passing made me go for it.
"He's a fantastic example that no matter how tall you are, it's about how good you are."
