Ronald Koeman's side came into the game on a poor run of form in the league that had seen them lose back-to-back games away at Chelsea and at home to Tottenham.
They were also beaten 3-0 away at Atalanta in their opening Europa League fixture on Thursday.
And their misfortunes continued today in Manchester with goals from Antonio Valencia, Henrikh Mkhitaryan, ex-Everton man Romelu Lukaku and Anthony Martial making it a 4-0 drubbing.
The Toffees have now lost four games on the spin in the Premier League and have failed to win since their opening day defeat of Stoke.
But which players disappointed in particular for them?
CLICK THROUGH THE GALLERY ABOVE TO SEE OUR EVERTON PLAYER RATINGS FOR THEIR DEFEAT AT MANCHESTER UNITED.
