The former Arsenal star believes the England forward has qualities Sergio Aguero, Romelu Lukaku and Alvaro Morata all lack.
All four of the hitmen netted last weekend in the Premier League for Spurs, Manchester City, Manchester United and Chelsea respectively.
But Merson would want only one of the four in his side if he had to pick.
He told Sky Sports: “I’m going to go for Kane. I think he's got everything. He plays up front on his own, he brings other players into the game.
“Don't get me wrong I'm a big Aguero fan, but if I'm going one up top away from home then Kane is the one who can hold his own.
“He has a fantastic temperament as well, he plays all the time and scores important goals, whereas Aguero will get four goals against weaker teams or score later in games.
“That's coming from a former Arsenal man so that's how highly I think of him.
“I don't think Lukaku has the all-round game. He'll score if you put it in the box but he doesn't bring other players in.
“Morata looks like a proper player but he's still got a lot to prove.”
Kane won the Golden Boot last season but is currently two goals behind Morata, Lukaku and Aguero in the early stages of the campaign.
Aguero and Kane are both in action this evening in the Champions League against Shakhtar Donetsk and Apoel Nicosia respectively.
