The Sweden international was thrown on in the centre of defence at the John Smith’s Stadium on Saturday after Phil Jones picked up an injury.

But Lindelof had a day to forget - hesitating in the build-up to Aaron Mooy’s opener for the Terriers, then seeing a weak header pounced on by Laurent Depoitre for the second goal as the Red Devils lost 2-1.

United boss Jose Mourinho has been reluctant to use his £30.75m summer buy from Benfica in the Premier League this season, suggesting last month that the defender needed time to adjust to the English game.

But with Jones struggling to recover from the thigh muscle injury he picked up on Saturday and Eric Bailly still battling a groin problem, Lindelof is set for another chance.

Mourinho was furious with United’s display as a whole at Huddersfield, which saw them slip five points behind Premier League leaders Manchester City.

Forward Juan Mata says United need a major improvement at the Liberty Stadium as they look to bounce back from their first league defeat of the campaign.

Victory in south Wales tonight would put cup holders Manchester United into the quarter-finals for the sixth time in nine seasons.

“It’s time to show that Saturday’s slip up is an isolated case, and that we remain in the same good direction we took at the beginning of the season,” said Mata.

“A defeat is unusual for us this season. We were on a very positive run of results but we didn’t play a good game and we came home with no points.

“We knew this moment would arrive sooner or later, although that’s something you never wish for, of course.

“Now, it’s time to learn from mistakes and keep going, as we always do, showing that the team sticks together when things don’t go so well, which is when we need it most.”