With 12 games gone, the Premier League season is really starting to take shape.

The top six has a very familiar feel to it and league leaders Manchester City will look to continue their outstanding start with a visit to a Huddersfield side sitting 10th at present.

Manchester United will expect to see off another of the promoted clubs, Brighton, as they seek to keep themselves on the coattails of Pep Guardiola's men.

The biggest game of the weekend sees Liverpool host champions Chelsea at Anfield, with Mohamed Salah desperate to show the Blues what they're missing; he takes on his former club for the first time in England as the Premier League's leading goalscorer.

Elsewhere. Crystal Palace are desperate for a win, Arsenal face Burnley at Turf Moor, Gary Megson leads out West Brom at Wembley and it all kicks off with David Moyes' first home game as West Ham boss.

Here's 10 things to keep an eye on...

1. All about reactions at London Stadium

David Moyes makes his home debut (
Image:
Reuters)

The weekend kicks off on Friday night with David Moyes' home bow as West Ham manager.

The Scot saw his side beaten in his opening game, going down 2-0 at Watford, leading to Moyes directing his fury at his players: "There were some players with big reputations who disappointed me.

“There were some who I thought would show me more, and why they play for the team regularly. They need to show me, 'If that's your reputation, show me why you've got it.' Overall, that level of performance will not be good enough.”

West Ham fans have hardly been overjoyed with Moyes' arrival, largely regarding him to be something of a busted flush after his spells at Manchester United, Real Sociedad and Sunderland all proved underwhelming.

What reaction will they give him at the London Stadium? More pertinently, what reaction will he get from his troops?

2. Salah shows Chelsea what could have been

Salah is the Premier League's top scorer right now (
Image:
Liverpool Echo)

Mohamed Salah only played 13 Premier League games for Chelsea, and he could hardly be in better form as he takes on his former employers in what will be his 13th for Liverpool.

The Egyptian was never really allowed to settle at Stamford Bridge when he joined in January 2014, lasting only a year before being packed off on loan to first Fiorentina and then Roma.

But since joining the Reds in the summer, his fortunes have dramatically improved.

As the jewel in the crown of Jurgen Klopp's attacking side, Salah has scored 14 times in 19 appearances in all competitions, with his nine Premier League strikes seeing become the unlikely leader in the race for the Golden Boot.

He'll be determined to get one over on his former club at Anfield, where Liverpool know that a win will put them level on points with the Blues.

3. More from record breaker Gabriel Jesus

Gabriel Jesus has the Terriers in his sights (
Image:
AFP)

It is now 13 months since Gabriel Jesus last tasted defeat in a competitive fixture, in a Brazilian league fixture against Santos. Back then, the Brazil striker was still largely unknown in the UK, playing for Palmeiras.

Since arriving at the Etihad he has been sensational, for both club and country, and is now some 43 games without defeat in competitive matches.

The 20-year-old has eight goals in the league so far this term, the same as Sergio Aguero and one more than Raheem Sterling, with Pep Guardiola's men blazing a trail at the top of the Premier League.

They head to the John Smith's Stadium this weekend as huge 2/11 favourites, largely thanks to their strike power and the Brazilian is very much the present and the future at the Etihad; City, and he, will take some stopping.

4. Zlat's back...but what about Lukaku?

The goals have dried up in recent weeks (
Image:
Action Images via Reuters)

It was perhaps the most interesting aspect of the entire 90 minutes during Manchester United's win last weekend; Zlatan Ibrahimovic arriving as a substitute and immediately pushing Romelu Lukaku, United's £75million No.9, over to the right wing.

He didn't say 'the big man's back, so step aside' but he may as well have done.

Again in the midweek defeat to Basel, the same happened once more. This time however, rather than United being comfortable and winning, with Lukaku having already scored, they were instead at 0-0, with the Belgian having missed a couple of good chances.

Lukaku's goal against the Magpies last weekend was his 12th of the season, but he has only one in his last nine club matches now. With Ibrahimovic back to full fitness, the pressure is on Lukaku to rediscover his early season form.

Jose Mourinho's treatment of Henrikh Mkhitaryan has shown that he's not afraid to drop his big-money signings when they aren't doing the business. Lukaku has been warned.

5. Newcastle look to get back on track

Benitez's side have suffered three straight defeats (
Image:
Andrew Powell)

Amid takeover talk, it has gone somewhat unnoticed that Newcastle have run into something of a brick wall of late.

Having started the season brightly with 14 points from nine games, Rafa Benitez's side have lost three on the spin, including a 4-1 loss at Manchester United in their last league game.

In both the last two games, Benitez has opted for a 4-4-2 formation rather than his preferred 4-2-3-1 shape and it hasn't really worked; Joselu and Dwight Gayle were paired together at Old Trafford, but the Magpies missed Ayoze Perez's ability to find space and link play between the lines.

With Isaac Hayden suspended and Jack Colback very much out in the cold, Benitez will hope Mikel Merino is fit to return, the Spaniard having made a bright start to the season, with his passing instrumental during Jonjo Shelvey's suspension.

6. Megson making his own moves

Gary Megson is back in charge at West Brom (
Image:
2017 Getty Images)

The king is dead. Long live the king.

Well not quite for West Brom fans, who have largely rejoiced following the sacking of Tony Pulis. Originally a marriage of convenience, Baggies fans never quite fell for the ex-Stoke and Crystal Palace manager's charms - not to mention 'Pulisball'.

Now Gary Megson - manager when they were promoted in 2001-02 - is in caretaker charge, and has already made his presence felt on the training ground; Megson has cast aside coach Ben Garner, 36, telling him he's not wanted after a clash over coaching methods (amid rumour of a player revolt, which the club insist is not the case).

Megson is going his own way, and insists there is more to come from his players: "There are some good players not playing too well. They have to step up. They will be given the opportunity and they have to start playing like we know they can play."

He would have hoped for an easier start than Tottenham away, but the Baggies boss be hoping to get a reaction, regardless of the result.

7. Crystal Palace can't let another must win get away

Palace's performances have improved, now results must do likewise (
Image:
2017 Getty Images)

So far this season, Crystal Palace's home record stands at one win, two draws and three defeats.

In itself, that isn't great, but when you look at the sides who they have faced at Selhurst Park - Huddersfield, Swansea, Southampton, Chelsea, West Ham and Everton - it looks far worse; four of those sides are expected (now) to be in the relegation mix come May.

With zero points and zero goals scored away from home, it is imperative for Roy Hodgson that his side's home form picks up.

Already they are five points from 17th and they now enter what looks set to be a defining run, with Stoke on Saturday followed by Brighton (A), West Brom (A), Bournemouth (H), Watford (H), Leicester (A) and Swansea (A). It's a run of seven games where they must be hitting 10-points plus.

Palace's performances have improved under Hodgson and now their results must do likewise. Three points from inconsistent Stoke would be the ideal start.

8. Swansea must solve strike woes

Paul Clement is facing a relegation fight with the Swans (
Image:
Getty)

With only two goals scored in their last five games, Swansea are struggling for goals.

Tammy Abraham, on loan from Chelsea, may have bagged four times in his 12 outings, but the side as a whole has only managed seven thus far; quite simply, they will be relegated if it continues.

Paul Clement and the board made big decisions in letting Gylfi Sigurdsson and Fernando Llorente go in the summer, and are now paying the price.

They need more from Wilfred Bony and the support cast against a Bournemouth side who have scored at least twice on each of their last four visits to the Liberty Stadium.

9. Arsenal must back up derby success

Ozil and Sanchez shone in the win over Spurs (
Image:
Action Images via Reuters/Paul Childs)

If Arsenal's north London derby success over Spurs was the Gunners' at something like their best, then now they must back it up.

Arsene Wenger's men have lost four times in their opening 12 Premier League matches, but remain level on points with Liverpool, one point off Spurs and just four points off second place Manchester United; they remain very much in the top four race.

Now, having got themselves up for the game last weekend, Messrs. Ozil, Sanchez and their pals must do so against one of the league's lesser lights, Burnley, in what is unquestionably a banana skin.

Arsenal have won the two sides' previous six meetings, but the Clarets have taken five points off Chelsea, Liverpool and Spurs this term, and are tough to beat. Turf Moor has seen only seven goals in its six league games so far.

With Arsenal, the talent isn't in question, but rather it is a continual question about mentality and decision making. They will dominate possession against Sean Dyche's men, but will they have the patience necessary to both find the breakthrough and stay defensively secure if an early goal isn't forthcoming.

There is every chance Arsenal could be frustrated for long spells and they must not allow that to lead to a downfall in Lancashire.

10. Unsworth's last stand

It's been difficult for Unsworth (
Image:
Alex Livesey)

If being a caretaker boss is something of an audition to become the No.1, then David Unsworth's tryout has been a write-off.

Such has been his failure to get anything that even remotely resembles a tune from his side, that you wonder whether any clubs within the Football League pyramid will ever look at the ex-defender for a manager's position again.

Unsworth can point to playing a number of youngsters, the fightback against Watford and the draw at Crystal Palace, but the thrashings by Lyon and now Atalanta, plus the non-showing at Leicester really do stick out like a sore thumb.

Farhad Moshiri says Everton are "close" to a new boss and Unsworth found out on radio that he was no longer in the running - a matter of hours before his Friday press conference.

While that's hardly the ideal way for him to find out, it is the right decision; the Toffees desperately need a new man through the door.