Alexis Sanchez has been dropped by Arsenal boss Arsene Wenger as his move to Manchester United nears closer.
Midfielder Jack Wilshere features for Arsenal against his old loan side but Mesut Ozil misses out through injury.
Aaron Ramsey is back in the squad following a hamstring issue.
For Bournemouth, Eddie Howe has left Andrew Surman — linked with a move to West Ham — out of the starting lineup.
You can see the teams in full below:
Bournemouth XI: Begovic, Francis, Cook, Ake, Smith, Cook, Gosling, Daniels, Ibe, Fraser, Wilson.
Subs: Boruc, Surman, Pugh, Arter, Afobe, Mousset, Simpson.
Arsenal XI: Cech, Chambers, Mustafi, Holding, Bellerin, Xhaka, Wilshere, Maitland-Niles, Iwobi, Welbeck, Lacazette.
Subs: Ospina, Mertesacker, Ramsey, Walcott, Kolasinac, Elneny, Nketiah.