Saturday 4 November 2017 14:49, UK
Manchester United travel to Stamford Bridge looking to end their poor run away at Chelsea. We take a look at this weekend's questions.
Stoke City kick the weekend off on Saturday lunchtime when they host Leicester City at the bet365 Stadium live on Sky Sports Premier League on Saturday before four games at 3pm.
Liverpool travel to West Ham in the late Saturday kick-off, before a real treat on Nissan Super Sunday as leaders Manchester City take on Arsenal before Chelsea face Manchester United at Stamford Bridge.
But what are the questions that will be answered this weekend? We take a look...
A vital 1-0 victory over Watford on Saturday, thanks to Darren Fletcher's first Premier League goal in his last 26 appearances, has eased the pressure on manager Mark Hughes.
With the significant victory under their belt, Stoke will be looking to record back-to-back wins in the Premier League for the first time since last November in Saturday's early kick-off. Their first win when they achieved that last season? A 1-0 away victory at Watford.
For Leicester, recently-appointed manager Claude Puel will be aiming to make it two wins out of two after a convincing 2-0 victory over Everton in last weekend's Super Sunday.
October was a disappointing for Tony Pulis' side as West Brom failed to record a single league victory for the second consecutive month despite a valiant effort in their 3-2 defeat to leaders Manchester City at the weekend.
Their last league win was on August 19, so West Brom will be desperate for victory at a Huddersfield side looking to record back-to-back home wins in the top flight for the first time since November 1971.
Huddersfield have won four of their last five home games, including that historic 2-1 triumph over Manchester United on October 21, so West Brom are look set for a tough afternoon.
Newcastle succumbed to a disappointing 1-0 loss to Burnley at Turf Moor on Monday Night Football with manager Rafael Benitez citing a "lack of precision" for their narrow defeat. But now the Spaniard's side will look to set the record straight against Bournemouth, who won their last Premier League away game at Stoke.
Victory at St James' Park could lift Bournemouth out of the bottom three, but Eddie Howe's men have made their worst start to a Premier League campaign with just seven points after 10 matches, and scored twice the number of goals at this stage in both their previous Premier League seasons (12 compared to six).
Sean Dyche led Burnley to a gritty 1-0 victory over Newcastle on Monday night, but now he has to face Southampton who have won their last four home games against his side in all competitions.
In Burnley's last 16 visits down to the south coast club, they have won just once back in 2008. So history says this should be another victory for Southampton, but Burnley are three places above their opponents in the table.
After Southampton's 1-1 draw with Brighton, manager Mauricio Pellegrino told Sky Sports he sums their season up as one "with ups and downs" so we should be in for an exciting encounter.
Swansea have won just one of their last seven Premier League matches and have scored just seven goals this season, with only Bournemouth and Crystal Palace having scored less. There has also been a reliance on 20-year-old striker Tammy Abraham, with the Chelsea loanee contributing to 71 per cent of their goals.
But now they enter a crucial period of matches against Brighton, Burnley and Bournemouth with fans hoping they can secure some vital points in their battle to avoid relegation.
Brighton drew 1-1 with Southampton on Sunday with Lewis Dunk admitting last season's Sky Bet Championship winners are now feeling "more relaxed" in the Premier League. But Pascal Gross has contributed to 70 per cent of their goals this season, so he will surely be looking to outshine Abraham on Saturday.
Liverpool have been handed an injury boost as three of West Ham's centre backs are considered doubts ahead of Saturday evening's clash with their manager Slaven Bilic still under pressure.
James Collins, Winston Reid and Jose Fonte are all set to miss out, while starting fullback Pablo Zabaleta will be suspended after picking up his fifth yellow card of the season against Crystal Palace.
Youngster Declan Rice or midfielder Cheikhou Kouyate may partner Angelo Ogbonna in central defence, which could give Liverpool boss Jurgen Klopp reason for optimism.
Liverpool bounced back from their heavy defeat to Tottenham with a 2-0 victory over Huddersfield on Saturday and will feel confident entering the contest at the London Stadium where they beat West Ham 4-0 last season.
Crystal Palace travel to Wembley Stadium to take on Tottenham Hotspur on Sunday afternoon hoping to score their first away goal in the Premier League this season.
Incredibly, bottom-of-the-table Palace have failed to net in any of their opening five league games on the road.
Only one team has ever failed to register a goal in their first six encounters on their travels in a season, however, with Derby County failing to find the back of the net in their opening eight away contests in the 2007/08 campaign, which saw them relegated with just 11 points.
In fact, the Eagles have actually not scored in any of their last seven away fixtures, a run stretching back 646 minutes since Christian Benteke was on target at Liverpool in April.
So, what better place to end that drought than at the home of football this weekend?
Arsenal will be desperate to repeat their win at the Etihad from January 2015 when they travel to take on Premier League leaders Manchester City on Super Sunday.
That 2-0 victory over City remains the Gunners' only away Premier League victory against the 'big six' since the start of the 2014/15 season, a dreadful run that includes nine defeats.
However, if Arsene Wenger's side can become the first team to get the better of City this season, then it would send out a huge statement about their title ambitions this campaign.
Chelsea will be looking to continue their impressive recent home form against Manchester United in their Super Sunday showdown this weekend.
The Premier League champions have lost just one of their last 15 Premier League games against the Red Devils at Stamford Bridge, with that solitary defeat coming in Sir Alex Ferguson's final season in charge of the club.
However, if Jose Mourinho is to triumph on his return to west London, then the United manager will need Romelu Lukaku - who is also facing his former club - to improve on a record of only 15 goals in 59 league games against 'big six' opposition.
Struggling Everton will be looking to avoid a third straight home defeat in the Premier League when they entertain Watford on Sunday afternoon.
The Toffees have not suffered three consecutive top-flight losses at Goodison Park since March 2016, when former manager Roberto Martinez was at the helm.
However, if caretaker boss David Unsworth wants to get the job on a full-time basis, then he will need to get the better of a Hornets side who have collected just one point from their previous 10 league visits to Everton.
