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Premier League odds 2017: Matchweek 16 betting preview and analysis for top games

Manchester City hosts Manchester United as a road betting favorite at the sportsbooks in the Manchester Derby this Sunday at Old Trafford.

Huddersfield Town v Manchester City - Premier League Photo by Shaun Botterill/Getty Images

Manchester City is undefeated with a 14-0-1 record through its first 15 games. That unbeaten streak will be put to the test this Sunday when City faces Manchester United in the latest installment of the Manchester Derby.

Manchester City is a +115 road favorite in Old Trafford at sportsbooks monitored by OddsShark.com. Manchester United is in the rare spot of being a home underdog at +230 while draw odds in this game are going off at +245. City has actually enjoyed a decent amount of success with a 4-1-1 record in its last six league games at Old Trafford — before this run, United was 15-1-11 in its previous 27 league home games against Manchester City.

Something will have to give in this one. Manchester City, the clear favorite on the EPL championship odds, has been the league's best road team with a perfect 7-0-0 record and a goal differential of +14 with 18 goals scored and only four against. However, Manchester United has looked nearly invincible at home with a 7-0-0 record while outscoring opponents 20 to 1.

In the last 12 league games between Manchester City and Manchester United, City holds a decisive 7-3-2 advantage.

Sergio Aguero's eight goals are tied for the fifth most all-time in this rivalry. The striker will be trying to narrow the gap with Wayne Rooney in the top spot with 11.

This will be the late game on Sunday. Two other top-five teams in the table are in action earlier in the day on Sunday as Liverpool (-360) hosts Everton (+950 to win, +475 to draw) and Arsenal (-110) visits Southampton (+290 win, +260 draw). Arsenal has had its share of struggles on the road this season with a 2-4-1 record away from home.

With the top-two teams in the English Premier League table clashing, Chelsea stands to gain some ground in the third spot with a road win. The Blues are 5-1-1 away from Stamford Bridge this season and are going off as -220 road favorites on Saturday at West Ham United (+600 win, +340 draw).

West Ham is just 3-17-4 in its last 24 games against Chelsea but has won each of its last two games against Chelsea at home.

English Premier League Betting Lines

Manchester United (+230) vs Man City (+115), Draw (+245)

Liverpool (-360) vs Everton (+950), Draw (+475)

Southampton (+290) vs Arsenal (-110), Draw (+260)

West Ham United (+600) vs. Chelsea (-220), Draw (+340)

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